Biotin deficiency is rare [ 12 , 18 ], and severe biotin deficiency in healthy individuals eating a normal mixed diet has never been reported [ 13 ]. The signs and symptoms of biotin deficiency typically appear gradually and can include thinning hair with progression to loss of all hair on the body; scaly, red rash around body openings eyes, nose, mouth, and perineum ; conjunctivitis; ketolactic acidosis which occurs when lactate production exceeds lactate clearance and aciduria abnormal amounts of acid in urine ; seizures; skin infection; brittle nails; neurological findings e.
Individuals with biotinidase deficiency Biotinidase deficiency is a rare autosomal recessive disorder that prevents the body from releasing free biotin, leading to biotin deficiency despite normal intake. Without treatment, biotinidase deficiency produces neurological and cutaneous symptoms, and profound biotinidase deficiency can lead to coma or death [ 19 , 20 ]. Individuals with chronic alcohol exposure Chronic exposure to alcohol inhibits the absorption of biotin [ 21 ].
Pregnant and breastfeeding women At least a third of pregnant women develop marginal biotin deficiency in spite of normal biotin intakes; plasma and breastmilk concentrations of biotin decrease in lactating women, even when their dietary biotin intakes exceed the AI [ 2 , 18 , 22 ].
Additional research is needed to understand the clinical significance of these findings. Signs of biotin deficiency include skin rashes, hair loss, and brittle nails [ 10 , 13 ]. Therefore, biotin supplements are often promoted for hair, skin, and nail health [ 16 , 23 , 24 ]. However, these claims are supported, at best, by only a few case reports and small studies. The evidence on biotin supplementation to treat brittle nails includes three small studies that did not include a placebo group, and these reports do not indicate the baseline biotin status of study participants.
One of these studies assessed the effects of 2. In the second study, 2. Finally, the third, retrospective study in 35 patients with brittle nails found that 2. Only case reports are available to support claims that biotin supplements can promote hair health, and these reports were only in children [ 28 , 29 ]. Future studies are needed to determine whether biotin supplements might improve hair, nail, and skin health, especially among healthy individuals. The FNB was unable to establish ULs for biotin because there is no evidence in humans that biotin is toxic at high intakes [ 1 ].
High biotin intakes, and potentially even intakes greater than the AI, may pose another type of health risk [ 32 ]. Supplementing with biotin beyond recommended intakes can cause clinically significant falsely high or falsely low laboratory test results, depending on the test. These incorrect results may lead to inappropriate patient management or misdiagnosis of a medical condition.
The following section has more details on these interactions. Very high intakes of biotin may interfere with diagnostic assays that use biotin-streptavidin technology and are commonly used to measure levels of hormones such as thyroid hormone and other analytes such as hydroxyvitamin D, producing falsely normal or abnormal results [ 9 , 32 ].
Even a single 10 mg dose of biotin has interfered with thyroid function tests administered within 24 hours of taking the supplement [ 38 ]. According to the Food and Drug Administration FDA , a patient with a high intake of supplemental biotin died following a troponin test to help diagnose a heart attack that gave a falsely low result because the test was subject to biotin interference [ 32 ]. FDA advises healthcare providers to ask their patients about any supplements they may be taking that contain biotin and to consider biotin interference as a possible source of error if laboratory test results do not match the clinical presentation of the patient [ 32 ].
Biotin can interact with certain medications, and some medications can have an adverse effect on biotin levels. One example is provided below. Individuals taking this and other medications on a regular basis should discuss their biotin status with their healthcare providers.
Anticonvulsants In a study in people with epilepsy, anticonvulsant treatment for at least 1 year was associated with significantly lower serum biotin levels than in control group patients [ 39 ]. A few other, smaller studies, have found similar results [ 40 , 41 ]. The reason could be that anticonvulsant treatment increases biotin catabolism, which leads to reduced biotin status and inhibition of intestinal biotin absorption [ 40 , 42 ]. The federal government's Dietary Guidelines for Americans notes that "Because foods provide an array of nutrients and other components that have benefits for health, nutritional needs should be met primarily through foods.
In some cases, fortified foods and dietary supplements are useful when it is not possible otherwise to meet needs for one or more nutrients e. For more information about building a healthy dietary pattern, refer to the Dietary Guidelines for Americans and the U. Department of Agriculture's MyPlate.
This fact sheet by the Office of Dietary Supplements ODS provides information that should not take the place of medical advice. Salmon is also packed with omega-3 fatty acids, which also happen to be great for people trying to make their hair healthier.
Healthy fats like this could help prevent hair loss. And it happens to be loaded with biotin. A 3-oz can 85 grams of tuna packed in water contains 0. Canned tuna is also high in omega-3 fatty acids and is an excellent source of protein, vitamin D, selenium, and iodine. Spinach is another vegetable that offers a decent amount of biotin. A 1-ounce gram serving of cheddar cheese contains 0. Certain meats can be a good source of biotin as well.
These include pork chops and cooked hamburger meat. A 3-ounce gram serving of both cooked pork chop and cooked hamburger meat contains 3. Biotin is a complex B vitamin that helps convert food into energy and aids in breaking down fat in our bodies. We typically get the biotin we need…. Preparation is power, and there are some vitamins and supplements that can support your immune health.
These don't hold any special magical powers…. Which foods can give your hair, skin, and nails a boost? Sweet potatoes and broccoli are also good sources and great accompaniments to your meat. Most dairy products are good sources and you can find biotin in milk, so adding it to coffee or drinking it with cookies can help you squeeze more biotin into your diet.
This can vary depending on the brand and the fat content of the milk you drink. In the US, the recommended biotin intake for adult men and women is 30 micrograms mcg a day. This is a recommended daily adequate intake though, the minimum amount needed to stay healthy, not a maximum amount.
If you consume large amounts, more than you need, your body can expel it easily. If you are interested in purchasing a prescription product from our website, FROM MARS will assist you with obtaining an independent doctor who will determine if the treatment is appropriate for you and consider writing a prescription for you which can be used at your pharmacy of choice.
About us. Medically proven treatments Erectile Dysfunction. Hair Loss. Genital Herpes. Valacyclovir Generic version of Valtrex Valtrex. You may already know that proteins and calcium are one of the most important nutrients for hair growth.
If you ever consult a dermatologist, they would suggest upping the intake of biotin too. Biotin is a B vitamin , which is known to convert ingested foods into energy. But, since it is a water-soluble vitamin, it is difficult to retain in the body and we need to replenish it regularly. There's a host of biotin supplements flying off the shelves of medical stores but there's nothing like getting our diet do the job naturally. So, if you are serious about putting an end to that dreadful hair loss and help your mane grow into healthy and gorgeous tresses, include these biotin-rich foods to your daily diet.
Dairy Products Milk, cheese, curd - all dairy products contain a good amount of biotin. These foods should be consumed on a daily basis for good health and great hair.
0コメント