However, as the different forms of MS are further studied, redefined, and reclassified, the label of progressive-relapsing MS is being used less frequently.
Other types of MS exist, but these are uncommon and different terminology may be used. Listed below are these less-common forms of MS. The first is clinically isolated syndrome CIS , where someone may have experienced symptoms of MS for the first time, and an MRI may show evidence of MS, but a diagnosis cannot be confirmed at that time. The diagnostic criteria for MS make it possible to diagnose MS in a person with CIS who also has specific findings on brain MRI that provide evidence of an earlier episode of damage in a different location and indicate active inflammation in a region other than the one causing the current symptoms.
In the meantime, individuals with CIS who are considered at high risk for developing MS may now be treated with a disease-modifying therapy that has been approved by the U. RRMS — the most common disease course — is characterized by clearly defined attacks of new or increasing neurologic symptoms. These attacks — also called relapses or exacerbations — are followed by periods of partial or complete recovery remissions.
During remissions, all symptoms may disappear, or some symptoms may continue and become permanent. However, there is no apparent progression of the disease during the periods of remission. Following a relapse, the new symptoms may disappear without causing any increase in level of disability, or the new symptoms may partially disappear, resulting in an increase in disability.
New lesions on MRI, as shown by the arrows, often occur as part of a relapse. However, new MRI lesions indicating MS activity may also occur without symptoms of which the person is aware.
SPMS follows an initial relapsing-remitting course. Some people who are diagnosed with RRMS will eventually transition to a secondary progressive course in which there is a progressive worsening of neurologic function accumulation of disability over time.
Some people may feel and seem healthy for many years following diagnosis, while others may be severely debilitated very quickly. Most people fit somewhere between these two extremes. Although every individual will experience a different combination of MS symptoms , and it is hard to predict how MS will affect a person over their lifetime, there have been four basic types of MS identified relating to the course of the disease.
Clinically Isolated Syndrome CIS is the first episode of neurological symptoms experienced by a person, lasting at least 24 hours.
The person may experience a single sign or symptom, or more than one at the same time. As such, it can be helpful to understand the characteristics and symptoms of MS at the time of initial diagnosis — particularly since the vast majority of people with the disease exhibit characteristics of relapsing-remitting MS. Identifying MS early at the relapsing-remitting stage can help ensure prompt treatment to avoid developing more progressive forms of the illness. Multiple sclerosis MS can cause immediate symptoms or longer-term issues that arise slowly over time.
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